Table 5.

Counts and risk estimates for BMI, weight gain, and height in relation to incident colon and rectal cancers, stratified by sex

MeasureCases
Controls
Colon cancer: case-control
Rectal Cancer: case-control
Colon cancer
Rectal cancer
n (%)Multivariable adjusted OR (95% CI)*
n (%)
Women
    BMI 2 y ago (kg/m2)
        18.5-24.99436 (44.7)178 (41.9)545 (45.3)11
        25-29.99304 (31.2)139 (32.7)384 (31.9)0.94 (0.77-1.16)1.19 (0.91-1.57)
        30+179 (18.3)80 (18.8)224 (18.6)0.91 (0.71-1.16)1.00 (0.72-1.39)
    BMI at age 20 y (kg/m2)
        18.5-24.99686 (70.3)309 (72.7)875 (72.7)11
        25-29.9968 (7.0)32 (7.5)92 (7.7)0.85 (0.60-1.20)0.96 (0.61-1.52)
        30+27 (2.8)11 (2.6)27 (2.2)0.98 (0.55-1.73)0.89 (0.42-1.88)
    Weight gain since age 20 y
        Weight loss72 (7.4)35 (8.2)85 (7.1)1.16 (0.79-1.71)1.27 (0.78-2.07)
        1-5 kg168 (17.2)88 (20.7)243 (20.2)11
        6-10 kg161 (16.5)67 (15.8)210 (17.5)1.15 (0.86-1.54)0.93 (0.63-1.37)
        11-20 kg275 (28.2)111 (26.1)349 (29.0)1.15 (0.88-1.49)0.96 (0.68-1.35)
        21+ kg220 (22.5)91 (21.4)258 (21.5)1.21 (0.92-1.60)1.00 (0.69-1.45)
    Height (m)
        <1.55134 (13.7)50 (11.8)220 (18.3)11
        1.65 > height ≥ 1.55428 (43.9)203 (47.8)528 (43.9)1.38 (1.06-1.79)1.73 (1.20-2.48)
        175 > height ≥ 1.65346 (35.5)150 (35.3)409 (34.0)1.50 (1.15-1.96)1.62 (1.11-2.37)
        ≥1.75 m61 (6.3)18 (4.2)42 (3.5)2.56 (1.61-4.08)1.61 (0.83-3.15)
Men
    BMI 2 y ago (kg/m2)
        18.5-24.99178 (22.0)119 (24.9)441 (30.1)11
        25-29.99394 (48.8)229 (47.9)738 (50.4)1.38 (1.10-1.72)1.15 (0.88-1.49)
        30+210 (26.0)111 (23.2)264 (18.0)2.04 (1.56-2.66)1.41 (1.02-1.95)
    BMI at age 20 y (kg/m2)
        18.5-24.99496 (61.4)284 (59.4)1,022 (69.8)11
        25-29.99183 (22.7)111 (23.2)273 (18.6)1.33 (1.06-1.66)1.35 (1.03-1.77)
        30+33 (4.1)17 (3.6)29 (2.0)2.05 (1.21-3.50)1.60 (0.83-3.07)
    Weight gain since age 20 y
        Weight loss45 (5.6)30 (6.3)86 (5.9)1.16 (0.76-1.79)1.11 (0.67-1.84)
        1-5 kg129 (16.0)84 (17.6)296 (20.2)11
        6-10 kg126 (15.6)78 (16.3)269 (18.4)1.11 (0.81-1.51)1.00 (0.70-1.45)
        11-20 kg224 (27.7)127 (26.6)443 (30.2)1.26 (0.96-1.66)1.06 (0.76-1.47)
        21+ kg213 (26.4)118 (24.7)305 (20.8)1.77 (1.33-2.37)1.46 (1.03-2.06)
    Height (m)
        <1.6533 (4.1)19 (4.0)54 (3.7)11
        1.75 > height ≥ 1.65247 (30.6)161 (33.7)490 (33.5)0.87 (0.54-1.40)1.01 (0.56-1.81)
        1.85 > height ≥ 1.75412 (51.0)224 (46.9)739 (50.4)0.96 (0.60-1.54)0.98 (0.55-1.74)
        ≥1.85107 (13.2)63 (13.2)175 (12.0)0.97 (0.58-1.64)1.18 (0.63-2.24)
  • NOTE: Some counts do not add to totals because of missing and omitted information.

  • * In men and women, adjusted for age, education, red meat intake, recreational physical activity, province of residence, CRC screening endoscopy, and history of high cholesterol/triglycerides. In women only, additionally adjusted for menopausal status and ever use of postmenopausal hormones.