Characteristics of E2 assays used in large epidemiologic studies of bone health in postmenopausal women
Study | Assay method | E2 detection limit (pg/mL)* | Lowest E2 tertile or quartile (pg/mL)* |
---|---|---|---|
Cummings et al., 1998 (1) | Extraction/chromatographic RIA† | 5 | <5 (quartile) |
Ettinger et al., 1998 (2) | |||
Garnero et al., 2000 (3) | Extraction/RIA‡ | 3 | <11 (quartile) |
Goderie-Plomp et al., 2004 (4) | Direct immunoassay§ | 1.3 | <11 (tertile) |
Rapuri et al., 2004 (5) | Direct immunoassay§ | 2.2 | 7.1 ± 0.14 (tertile)∥ |
Ettinger et al., 2004 (6) | Direct immunoassay¶ | 1.4 | <2.7 (quartile) |