Table 3.

Effects of genetic and environmental factors in melanoma and SCC

Single-trait modelGeneticFamily-shared environmentChildhood-shared environment
Variance component estimates (95% CI)
Melanoma, all sites0.25 (0.20-0.32)0.09 (0.06-0.11)0.11 (0.05-0.18)
    Exposed sites0.16 (0.08-0.25)0.08 (0.05-0.11)0.11 (0.02-0.21)
    Covered sites0.18 (0.07-0.30)0.12 (0.08-0.16)0.13 (0.02-0.25)
SCC, all sites0.11 (0.05-0.17)0.26 (0.24-0.28)0.10 (0.04-0.17)
    Exposed sites0.12 (0.06-0.19)0.26 (0.24-0.28)0.11 (0.03-0.17)
Percentage of variance (95% CI)
Melanoma, all sites18 (13-22)6 (4-7)8 (3-12)
    Exposed sites12 (6-18)6 (3-8)8 (1-15)
    Covered sites13 (5-21)9 (6-11)9 (1-17)
SCC, all sites8 (4-12)18 (16-19)7 (3-11)
    Exposed sites8 (4-13)17 (16-19)7 (2-12)