Table 1.

Demographics and clinical characteristics (N = 106)

VariableBRCA1 del (ex 9-12) mutation status
CarrierNoncarrier
n (%)4 (3.8%)102 (96.2%)
Gender
    Male01 (0.1%)
    Female4 (100%)101 (99.0%)
Cancer status
    Unaffected (%)05 (4.9%)
    Affected with BC and/or OC (%)4 (100%)97 (95.1%)
        BC (%)3 (75.0%)77 (79.4%)
        Bilateral BC1 (25.0%)10 (10.3%)
        OC (%)04 (4.1%)
        BC and OC (%)03 (3.1%)
        DCIS (%)03 (3.1%)
Average age at first BC diagnosis ± SD37.0 ± 3.637.9 ± 8.0
Probands' parental country(ies) of origin*
    No. Mexican (%)3 (75.0%)66 (64.7%)
    No. Central American/Caribbean (%)014 (13.7%)
    No. South American (%)03 (2.9%)
    No. Spanish (%)02 (2.0%)
    No. mixed (%)1 (25.0%)17 (16.7%)
  • Abbreviations: BC, breast cancer; OC, ovarian cancer; DCIS, ductal carcinoma in situ.

  • * Applies to both parental lineages; except those with mixed ancestry indicated in the last category.

  • “Mixed” means a combination of above or combination of Hispanic and non-Hispanic ancestry.