Table 4.

ORs and 95% CIs for bladder cancer according to family history of selected cancers

Family-history cancer siteCases (n = 1,158)Controls (n = 1,244)OR* (95% CI)
None694808Reference (—)
All sites4644361.32 (1.11-1.59)
Urinary bladder1692.34 (0.95-5.77)
Tobacco-associated sites1681251.69 (1.28-2.23)
Non–tobacco-associated sites3002881.18 (0.96-1.44)
Lip, oral cavity, and pharynx11101.34 (0.53-3.40)
Esophagus1682.73 (1.07-6.97)
Stomach54571.10 (0.72-1.68)
Intestine38480.93 (0.58-1.49)
Liver40461.04 (0.65-1.67)
Pancreas14101.43 (0.60-3.44)
Larynx24231.46 (0.77-2.79)
Lung90671.64 (1.14-2.36)
Bone10110.90 (0.36-2.26)
Female breast57431.50 (0.95-2.37)
Uterus, unspecified18191.41 (0.70-2.84)
Ovary5100.75 (0.25-2.31)
Prostate43292.15 (1.28-3.61)
Kidney561.12 (0.30-4.09)
Brain1362.88 (1.00-8.27)
All lymphomas321.83 (0.27-12.5)
Leukemia, unspecified19171.47 (0.71-3.02)
  • * After adjustment by unconditional logistic regression for age, gender, area, and smoking status of the subjects and average lifetime trihalomethane levels (μg/L).

  • Include cancers of the oral cavity and pharynx, respiratory organs, esophagus, pancreas, urinary bladder, and kidney.