Table 1.

Characteristics of 412 hepatitis B surface antigen–positive study participants

VariableMales (n = 229)
Females (n = 183)
P
n (%)n (%)
Age, mean ± SD (y)49.9 (9.0)49.9 (7.8)0.98
Alcohol consumption
    Current drinker116 (51)21 (11)<0.0001
    Nondrinker113 (49)162 (89)
Cigarette smoking
    Current smoker104 (45)4 (2)<0.0001
    Nonsmoker125 (56)179 (98)
HBV DNA
    Positive67 (29)30 (16)<0.0001
    Negative162 (71)153 (84)
HBV DNA
    Mean titre ± SD (copies/mL)595 ± 917585 ± 8000.24
    Mean titre ± SD (log10 copies/mL)2.2 ± 0.82.3 ± 0.70.24
Mean ALT ± SD (IU/L)41 ± 3925 ± 23<0.0001
Folate (μg/L)
    Mean serum folate ± SD9.1 ± 1.611.9 ± 1.5<0.0001
    Mean RBC folate ± SD366 ± 1.34436 ± 1.34<0.0001
HCC developed during study
    Yes12 (5.2)8 (4.4)0.68
    No217 (94.8)175 (95.6)