Table 1.

Adverse events in healthy volunteers after a single dose of resveratrol

Nature of event*No. individuals
Dose level (g)
0.51.02.55.0
Unlikely to be drug related
    Raised urea1010
    Raised creatinine1000
    Low total protein1000
    Raised albumin0001
    Raised phosphate2012
    Low phosphate0100
    Raised bilirubin0010
    Raised calcium1000
    Raised glucose1311
    Low CO20022
    Raised lactate dehydrogenase1001
    Low lactate dehydrogenase0001
    Raised cholesterol0200
    Low WBC count0010
    Raised neutrophil count0100
    Raised lymphocyte count0100
    Raised eosinophil count0001
    Low basophil count0010
    Raised platelet count1100
    Low hematocrit2000
    Raised chloride1101
    Cellulitic foot infection0100
    Flatulence0100
    Nausea0100
    Loose stool0200
    Panic attack0100
    Headache0110
Possibly drug related
    Raised bilirubin0200
    Raised alanine aminotransferase0100
  • * All (except where indicated) National Cancer Institute Common Toxicity Criteria grade 1.

  • National Cancer Institute Common Toxicity Criteria grade 2.

  • In one of these two individuals, event was National Cancer Institute Common Toxicity Criteria grade 2.