Table 3.

Multivariate Cox proportional hazard model of progression-free survival and overall survival (n = 93)

Progression-free survival
Overall survival
HR (95% CI)P*HR (95% CI)P*
Tumor stage
    pTa1.01.0
    pT131.6 (2.6-386.1)<0.0012.6 (1.0-6.7)0.04
Tumor grade
    G11.01.0
    G2/G31.7 (0.2-15.8)0.61.4 (0.5-3.9)0.5
Tumor history
    First event1.01.0
    Recurrent tumor3.6 (0.7-19.1)0.11.02 (0.4-2.5)0.9
Treatment
    Control1.01.0
    Fenretinide0.8 (0.2-3.2)0.70.8 (0.3-1.9)0.6
DNA index
    DNA index < 1.1 (diploid)1.01.0
    DNA index ≥ 1.1 (aneuploid)10.5 (1.1-126.1)0.032.8 (1.0-9.0)0.05
  • NOTE: The risk estimates are adjusted for age, smoking habit, and previous intravesical treatment.

  • * Two-sided likelihood ratio test.