Table 3.

Association between a history of coffee consumption and breast cancer risk by CYP1A2 genotype

Type of coffee/CYP1A2 genotypeControl, n (%)Case, n (%)OR (95% CI)*P
Total, AA
    Never41 (33.6)30 (35.3)1
    Ever81 (66.4)55 (64.7)0.93 (0.49-1.77)0.82
Total, AC or CC
    Never30 (25.2)36 (42.4)1
    Ever89 (74.8)49 (57.7)0.36 (0.18-0.73)0.005
  • * ORs and 95% CI adjusted for year of birth, age at menarche, parity (0, 1, 2, 3, or ≥4), and smoking history (ever/never).

  • Total refers to consumption of either caffeinated or decaffeinated coffee.