Table 1.

Distribution of genotypes among linked and unlinked affected sibs and among affected and unaffected individuals

Subgroup9A/9A9A/6A6A/6ATotal
Genotypes in affected individuals
    Linked31 (86%)4 (11%)1 (3%)36
    Unlinked12 (75%)4 (25%)016
    Unknown53 (87%)8 (13%)061*
    Total96 (85%)16 (14%)1 (1%)113
Distribution including individuals with small ademonas or late onset colon cancer as affected individuals
    Linked42 (82%)8 (16%)1 (2%)51
    Unlinked21 (75%)7 (25%)028
    Unknown33 (97%)1 (3%)034
    Total96 (85%)16 (14%)1 (1%)113
Genotypes in affected and unaffected individuals
    All affected individuals90241115 (27%)
    All unaffected individuals3612048 (25%)
    Affected siblings88231112 (21%)
    Unaffected siblings2610036 (28%)
  • * Two individuals in the unknown subgroup failed for genotyping at the TGFBR1 gene.

  • Indicates percentage of sample with one or more 6A alleles.