Table 2.

MMP-7 levels in plasma, pancreatic juice, and duodenal juice

Pathologic diagnosisPlasma
Pancreatic juice
Duodenal juice
NMedian MMP-7 (ng/mL)IQRPNMedian MMP-7 (ng/mg protein)IQRPNMedian MMP-7 (ng/mg protein)IQRP
Chronic pancreatitis270.830.60-1.2125249.1-144244.00.2-17.0
Pancreatic carcinoma281.991.25-3.43*1714343-456192.60.4-10.0
Distal cholangiocarcinoma101.830.81-4.076395.4-43880.90.2-1.5
Ampullary carcinoma91.990.66-2.76§8253.7-4692.00.3-4.9
Carcinoma other40.480.29-0.7941334.8-108040.30.2-0.6
Benign disease80.790.71-1.545181.0-6361.00.2-1.7
Carcinoma511.950.81-3.22356218-241401.30.3-4.6
No carcinoma350.830.25-1.2130238.5-99292.60.2-13.1
PD; CP at pathology51.160.79-2.163245.7-826413.30.2-25.5
  • Abbreviations: IQR, interquartile range (25-75%); PD, pancreaticoduodenectomy; CP, chronic pancreatitis.

  • * Compared with chronic pancreatitis (P < 0.01) and with benign disease (P < 0.047).

  • Compared with chronic pancreatitis (P = 0.04) and with benign disease (P = 0.03).

  • Compared with chronic pancreatitis (P < 0.01).

  • § Compared with chronic pancreatitis (P = 0.03).

  • Full range.

  • Compared with no carcinoma (P < 0.01).