Table 4.

Associations between CYP19A1 genotypes and endometrial cancer risk among postmenopausal women

BMI < 25
BMI ≥ 25
CasesControlsOR* (95% CI)CasesControlsOR* (95% CI)
rs1065779
    G/G911131.0100791.0
    G/T1291810.92 (0.67-1.25)1761241.17 (0.84-1.62)
    T/T40910.57 (0.37-0.87)52500.86 (0.54-1.35)
    Ptrend0.020.47
    Pinteraction = 0.27
rs700519
    C/C2102861.02251881.0
    C/T47890.72 (0.49-1.06)88561.32 (0.91-1.92)
    T/T2100.28 (0.06-1.27)741.46 (0.42-5.06)
    Ptrend0.030.15
    Pinteraction = 0.01
rs28566535
    A/A1211741.01281061.0
    A/C1161650.99 (0.73-1.35)1541141.16 (0.84-1.60)
    C/C25480.74 (0.44-1.24)45291.34 (0.80-2.23)
    Ptrend0.450.34
    Pinteraction = 0.22
rs752760
    T/T861381.01261051.0
    T/C1371831.1 7 (0.87-1.60)154941.47 (1.05-2.04)
    C/C36531.07 (0.67-1.59)42400.94 (0.58-1.52)
    Ptrend0.530.85
    Pinteraction = 0.76
rs1870050
    A/A1411771.01761191.0
    A/C971690.73 (0.54-1.00)1261030.92 (0.66-1.27)
    C/C17350.62 (0.34-1.14)20210.71 (0.38-1.36)
    Ptrend0.030.13
    Pinteraction = 0.69
  • NOTE: The number of participants does not add up to the total number of women because of missing data on genotypes for some participants.

  • * Unconditional logistic model adjusted for age.