Table 1.

Gene information and κ statistics for matched AML and buccal DNA samples (N = 80)

GeneSingle nucleotide polymorphism locationChromosomers nos.κAsymptotic errorConfidence intervalNo. of evaluable cases (%)No. of nonmatching genotype calls
ABCB1-03Ex27-55A>C>G>T; I1144M7q21.1rs10456421.0077 (96.3)0
ABCB1-05Ex22-9A>C>G>T; A892S7q21.1rs20325820.960.0310.89-1.0276 (95.0)2
ABCB1-24Ex13+12 A>G; G412G7q21.1rs11285030.980.0230.95-1.0276 (95.0)1
ABCC1Ex8 T825C; V275V16p13.1rs2462211.0076 (95.0)0
ABCC1Ex28 G4002A; S1334S16p13.1rs22306711.0078 (97.5)0
ABCC1Ex9 T1062C; L562L16p13.1rs355870.980.0220.93-1.0277 (96.3)1
ABCG2Ex5 C421A; Q141K4q22rs22311421.0075 (93.8)0
ABCG2Ex2 G34A; V12M4q22rs22311371.0075 (93.8)0
CAT-01−329T>C11p13rs10011791.0078 (97.5)0
GPX1-01Ex1-226C>T; P200L3p21.3rs10504500.960.0290.90-1.0279 (98.8)2
SOD2-01Ex2+24C>T; V16A6q25.3rs17997250.980.0200.94-1.0277 (96.3)1
GSTA1-01−4621T>C6p12.1rs39573571.0078 (97.5)0
GSTP1-01Ex5-24A>G; I105V11q13rs9478940.960.0300.90-1.0278 (97.5)2
GSTM1Gene deletion1p13.31.0077 (96.3)0
GSTT1Gene deletion22q11.231.0077 (96.3)0
CYP3A4-02−391A>G7q21.1rs27405740.940.0530.89-1.0577 (96.3)1
CYP2C8A1196G; R399K10q23.33rs105096810.960.0400.88-1.0477 (96.3)1
CYP2C8C792G; M264I10q23.33rs10589300.960.0410.88-1.0477 (96.3)1
MGMT-01Ex4-13A>G; I143V10q26rs23083211.0080 (100.0)0
XPD312Ex10-16G>A; D312N19q13.3rs17997931.0073 (91.3)0
XPD751Ex23-61A>C; K751Q19q13.3rs131810.980.0220.93-1.0276 (95.0)1
XRCC1Ex10-4A>G; Q399R19q13.2rs254871.0074 (92.5)0
CDAA79C; K27Q1p36.2-p35rs20726711.0077 (96.3)0
  • NOTE: Values of κ: κ > 0.75 (excellent agreement beyond chance), κ between 0.40 and 0.75 (fair to good agreement), κ < 0.40 (poor agreement).