Table 3.

Distribution of genotypes by sex and risk of lung cancer

UGT2B17 genotypeCases (%)Controls (%)OR (95% CI)*
Men
    (+/+)121 (54)176 (47)Reference
    (+/0)83 (37)156 (42)0.7 (0.4-1.1)
    (0/0)19 (9)41 (11)0.7 (0.4-1.5)
    (+/+) + (+/0)204 (91)332 (89)Reference
    (0/0)19 (9)41 (11)0.9 (0.4-1.7)
Women
    (+/+)91 (52)161 (50)Reference
    (+/0)58 (33)131 (40)0.8 (0.5-1.3)
    (0/0)26 (15)32 (10)1.8 (0.9-3.7)
    (+/+) + (+/0)149 (85)292 (90)Reference
    (0/0)26 (15)32 (10)2.0 (1.01-4.0)
  • * OR and 95% CI adjusted for age, BMI, education level, and pack-years.