Table 4.

Adjusted ORs for waist-to-hip ratio among colorectal adenoma cases, colonoscopy controls, and population controls; Minnesota Cancer Prevention Unit Case-Control Study, 1991-1994

WHRCases (n)Controls (n)OR (95% CI)Pheterogeneity*
Colonoscopy controls
All women
    <0.765 (reference)43981.00 (—)0.23
    0.765-<0.81842980.73 (0.42-1.25)
    0.818-<0.885661011.05 (0.63-1.74)
    ≥0.88550970.68 (0.40-1.17)
Premenopausal women
    <0.765 (reference)12501.00 (—)0.72
    0.765-<0.8188331.02 (0.35-3.03)
    0.818-<0.8859321.17 (0.41-3.30)
    ≥0.8856161.96 (0.59-6.54)
Postmenopausal women
    <0.765 (reference)30481.00 (—)0.07
    0.765-<0.81833670.58 (0.30-1.12)
    0.818-<0.88557700.85 (0.46-1.58)
    ≥0.88544810.48 (0.25-0.91)
Postmenopausal PMH users
    <0.765 (reference)20391.00 (—)0.28
    0.765-<0.81814490.46 (0.20-1.06)
    0.818-<0.88521410.83 (0.37-1.41)
    ≥0.88518420.62 (0.24-1.41)
Postmenopausal PMH nonusers
    <0.765 (reference)1291.00 (—)0.06
    0.765-<0.81821190.66 (0.21-2.06)
    0.818-<0.88536280.67 (0.23-1.92)
    ≥0.88526390.30 (0.10-0.88)
Population controls
All women
    <0.774 (reference)54591.00 (—)0.50
    0.774-<0.82537580.64 (0.36-1.15)
    0.825-<0.87957600.89 (0.51-1.55)
    ≥0.87953550.85 (0.48-1.51)
Premenopausal women
    <0.774 (reference)14271.00 (—)0.07
    0.774-<0.8256141.31 (0.28-6.12)
    0.825-<0.879995.26 (1.17-23.71)
    ≥0.879656.32 (1.17-34.20)
Postmenopausal women
    <0.774 (reference)39321.00 (—)0.20
    0.774-<0.82530440.50 (0.25-0.98)
    0.825-<0.87948510.58 (0.30-1.12)
    ≥0.87947500.58 (0.30-1.13)
Postmenopausal PMH users
    <0.774 (reference)23211.00 (—)0.23
    0.774-<0.82514270.41 (0.16-1.02)
    0.825-<0.87917230.47 (0.18-1.22)
    ≥0.87919230.50 (0.19-1.30)
Postmenopausal PMH nonusers
    <0.774 (reference)18111.00 (—)0.77
    0.774-<0.82518170.66 (0.24-1.84)
    0.825-<0.87931280.65 (0.26-1.65)
    ≥0.87928270.61 (0.24-1.57)
  • NOTE: ORs were adjusted for age, family history of colon cancer, family history of polyps, and pack-years of smoking.

    Abbreviation: WHR, waist-to-hip ratio.

  • * Breslow-Day test for heterogeneity of ORs.

  • Additionally adjusted for PMH use.