Table 4.

Quintile analysis of dietary mutagen intake and risk of pancreatic cancer

1*2345Ptrend
MeIQx0.14
    Median (case/control)7.46/7.6119.42/18.9835.33/32.6057.82/55.43129.77/129.48
    Range (control)0-13.9614.13-25.2625.41-43.6444.11-78.6779.34-679.06
    No. (case/control)138/10695/106107/106120/106166/106
    OR (95% CI)1.000.62 (0.42-0.94)0.73 (0.49-1.09)0.81 (0.54-1.20)1.11 (0.75-1.65)
DiMeIQx0.02
    Median (case/control)0/00.78/0.851.74/1.803.08/3.027.63/7.15
    Range (control)0-0.340.35-1.311.31-2.262.27-4.034.04-33.60
    No. (case/control)115/107127/10591/107109/105184/106
    OR (95% CI)1.001.09 (0.73-1.62)0.73 (0.48-1.10)0.86 (0.57-1.30)1.52 (1.03-2.25)
PhIP0.22
    Median (case/control)20.10/24.2264.67/61.48111.68/118.44219.76/221.54496.88/431.48
    Range (control)0-41.6341.64-84.4184.78-158.64158.93-304.99305.1-2,667.07
    No. (case/control)127/10692/106138/106127/106142/106
    OR (95% CI)1.000.84 (0.56-1.27)1.37 (0.92-2.02)1.10 (0.74-1.64)1.30 (0.87-1.94)
BaP0.19
    Median (case/control)1.23/1.5515.45/16.5736.98/37.3268.62/63.56164.56/156.65
    Range (control)0-6.356.78-26.6726.94-48.1248.87-95.2195.62-695.27
    No. (case/control)122/106118/106100/106141/106145/106
    OR (95% CI)1.000.93 (0.62-1.39)0.80 (0.53-1.21)1.35 (0.91-2.00)1.32 (0.89-1.97)
Mutagenicity0.10
    Median (case/control)1,419/1,6763,342/3,3925,427/5,4659,119/8,71618,611/17,006
    Range (control)0-2,4332,459-4,3324,340-6,7946,903-11,92011,934-76,495
    No. (case/control)125/106105/106109/106131/106156/106
    OR (95% CI)1.000.74 (0.49-1.11)0.87 (0.58-1.30)1.03 (0.70-1.54)1.17 (0.78-1.76)
  • * Quintiles of consumption from control group.

  • OR adjusted for age, race, sex, education, smoking, alcohol consumption, diabetes, pancreatitis, and family history of cancer.