Table 6.

Glioma and meningioma risks in relation to GSTP1 105 and GSTP1 114 genotype combinations suggested by Ali-Osman et al. (32) adjusted for sex, age, and country

Amino acids
Combined genotype allelesControls, nGlioma, nGlioma, OR (95% CI)Glioblastoma, nGlioblastoma, OR (95% CI)Meningioma, nMeningioma, OR (95% CI)
105114
Ile/IleAla/Alaaa6783371.001511.002451.00
Ile/ValAla/Alaab5431970.74 (0.59, 0.91)910.75 (0.56, 1.01)1680.91 (0.72, 1.15)
Ile/ValAla/Valac*165921.11 (0.82, 1.50)350.94 (0.62, 1.43)711.16 (0.84, 1.60)
Val/ValAla/Alabb108460.90 (0.61, 1.32)321.43 (0.91, 2.23)300.81 (0.52, 1.26)
Val/ValAla/Val or Val/Valbc or cc84461.13 (0.76, 1.69)181.01 (0.58, 1.75)240.74 (0.46, 1.21)
  • NOTE: Data from population-based case-control studies conducted in Sweden, southeast England, Denmark, and Finland (2000-2004).

  • * Not possible to distinguish from the very uncommon bd-genotype.