Table 1.

Infections associated with NHL

Infectious agentNHL subtype
Lymphocyte-transforming viruses
    Esptein Barr virusBurkitt's lymphoma
AIDS-associated NHLs
Posttransplant lymphoproliferative disorder
Extranodal natural killer/T-cell NHL
    Human Herpesvirus 8Primary effusion lymphoma and related DLBCL
MCD-associated plasmablastic NHL
    Human T lymphotropic virus type IAdult T-cell leukemia/lymphoma
Agents that cause immunosuppression
    Human Immunodeficiency VirusAIDS-associated NHLs
Agents that cause chronic immune stimulation
    Plasmodium falciparum*Burkitt's lymphoma
    Hepatitis C virusUncertain
    Helicobacter pyloriGastric MALT NHL
    Campylobacter jejuniSmall intestine MALT NHL
    Chlamydia psittaciOcular adnexa MALT NHL
    Borrelia afzeliiCutaneous MALT NHL
  • Abbreviation: MCD, multicentric Castleman's disease; AIDS, acquired immunodeficiency syndrome; DLBCL, diffuse large B cell lymphoma; MALT, mucosa-associated lymphoid tissue.

  • * The possible mechanism of action of P. falciparum malaria in causing Burkitt's lymphoma is not well characterized and may involve immunosuppression.