Table 1.

Comparison of cases and controls by selected demographic factors and major risk factors for endometrial cancer from the Shanghai Endometrial Cancer Study, 1997-2003

Subjects with genotyping data
P
Cases (n = 1,041)Controls (n = 1,030)
Age at diagnosis (y)*54 (48, 61)54 (48, 62)0.75
Education >high school (%)40.439.80.04
Marital Status (%)
    Single1.41.20.92
    Married87.087.7
    Widowed/separated/divorced11.611.0
Regular smoker (%)3.23.50.68
Regular alcohol consumption (%)3.15.5<0.01
First-degree relative with cancer (%)35.329.2<0.01
Age at menarche (y)*14 (13, 16)15 (13, 16)<0.001
Premenopausal (%)43.338.40.02
Age at menopause (y)*,50.3 (48.6, 52.5)49.5 (47.3, 51.1)<0.001
Years of menstruation*33.2 (30.1, 36.0)31.4 (28.1, 34.2)<0.001
No. pregnancies (%)
    None7.13.8<0.001
    117.113.4
    225.826.3
    322.525.7
    416.117.1
    5 or more11.313.7
Oral contraceptive use ever (%)18.425.1<0.001
HRT use ever (%)4.64.30.71
No regular physical activity (%)71.966.20.04
BMI*25.3 (23.0, 28.2)23.4 (21.4, 25.9)<0.001
Diagnosis of diabetes15.06.9<0.01
B vitamin supplement use (%)8.011.6<0.01
Folate intake (μg/d)*288.9 (231.0, 370.0)293.1 (227.7, 367.7)0.98
Riboflavin intake (mg/d)*0.89 (0.68, 1.12)0.88 (0.67, 1.10)0.11
Vitamin B6 intake (mg/d)*2.09 (1.64, 2.63)1.99 (1.57, 2.49)<0.01
Vitamin B12 intake (μg/d)*3.41 (2.27, 4.89)3.01 (1.95, 4.46)<0.01
Methionine intake (g/d)*1.88 (1.45, 2.41)1.75 (1.33, 2.26)<0.01
Total calorie intake (kcal/d)*1,739 (1,474, 2,048)1,711 (1,423, 2,012)0.04
Total animal food intake (g/d)*176.7 (120.7, 241.9)155.8 (103.8, 221.5)<0.01
Total fruit and vegetable intake (g/d)*510.3 (341.6, 699.0)488.4 (338.3, 684.1)0.32
  • Abbreviation: HRT, hormone replacement therapy.

  • * Median (25th, 75th percentile) is presented.

  • Among postmenopausal women.