Table 1.

Description of 151 high-risk pancreatic cancer families

Mayo Clinic, n = 41 (%)Johns Hopkins, n = 101 (%)Toronto, n = 9 (%)Total, n = 151 (%)
No. pancreatic cancers
    237 (90)77 (76)7 (78)121 (80)
    33 (7)16 (16)2 (22)21 (14)
    ≥41 (3)8 (8)0 (0)9 (6)
Family history of pancreatic cancer
    ≥2 First-degree relatives24 (59)89 (88)5 (56)118 (78)
    ≥2 Second-degree relatives17 (41)12 (12)4 (44)33 (22)
Other cancers
    Breast17 (41)32 (32)3 (33)52 (34)
    Ovarian5 (12)7 (7)0 (0)12 (8)
    Prostate13 (32)16 (16)0 (0)29 (19)
Proband age of onset
    ≤5512 (29)28 (28)3 (33)43 (28)
    >5529 (71)73 (72)6 (67)108 (72)