Table 3.

Z scores for disease pools compared with control distribution—premenopausal control with outlying CA 125 value excluded

GroupZ score*
CA 125CA 19.9CA 15.3CEA
Pelvic diseases
    Premenopausal, late stage, nonmucinous11.
    Postmenopausal, late stage, nonmucinous11.00.86.1−0.2
    Postmenopausal, early stage, nonmucinous7.
    Premenopausal/postmenopausal, mucinous4.
    Premenopausal/postmenopausal, endometrial cancer7.
    Premenopausal, endometriosis4.21.20.7≈ 0
    Postmenopausal, benign serous4.
Breast diseases
    Premenopausal, invasive1.
    Postmenopausal, ER+ invasive0.
    Premenopausal/postmenopausal, DCIS0.
    Premenopausal, benign0.30.6≈ 00.5
    Postmenopausal, benign0.
  • Abbreviations: DCIS, ductal carcinoma in situ; ER+, estrogen receptor positive.

  • * Z score = [log(value in pool) − mean(log(values in appropriate controls))] / SD(log(values in appropriate controls)).