Table 1.

Effect of key demographic and clinical characteristics on standard markers

Characteristicn (%)Mean marker levels (SD)
CA 125 (units/mL)CA 19.9 (units/mL)CA 15.3 (units/mL)CEA (ng/mL)SMRP (nmol/L)
Race
    White79 (83%)16.3 (1.8)10.4 (3.2)16.8 (1.5)1.8 (1.7)0.7 (1.6)
    Black11 (12%)10.9 (1.7)9.6 (4.4)14.9 (1.6)2.2 (1.8)0.5 (1.7)
    Other/unknown5 (5%)11.3 (1.2)5.9 (5.1)10.2 (1.5)2.4 (2.1)0.7 (2.0)
    Univariate P*0.050.610.030.290.19
    Multivariate P0.010.430.010.310.22
Menopausal status
    Premenopausal39 (41%)18.2 (2.0)7.5 (4.1)15.9 (1.6)1.6 (1.7)0.6 (1.5)
    Postmenopausal56 (59%)13.5 (1.6)12.2 (2.8)16.3 (1.5)2.1 (1.8)0.8 (1.6)
    Univariate P*0.010.060.810.02<0.01
    Multivariate P<0.010.060.840.010.01
Ever pregnant?
    Yes68 (72%)15.8 (1.9)10.7 (3.4)16.7 (1.5)2.0 (1.7)0.7 (1.6)
    No27 (28%)13.9 (1.5)8.2 (3.6)14.8 (1.6)1.5 (1.8)0.6 (1.5)
    Univariate P*0.350.340.180.020.12
    Multivariate P0.070.360.060.090.16
Ever smoked?
    Yes44 (46%)14.8 (1.6)10.2 (3.4)16.0 (1.6)2.3 (1.8)0.7 (1.6)
    No51 (54%)15.7 (2.0)9.7 (3.5)16.3 (1.5)1.5 (1.6)0.7 (1.6)
    Univariate P*0.630.840.82<0.010.56
    Multivariate P0.620.980.65<0.010.66
Overall9515.3 (1.8)10.0 (3.4)16.1 (1.5)1.8 (1.8)0.7 (1.6)
  • * P value from linear regression of individual characteristic on log-transformed marker values.

  • P value from linear regression of all characteristics on log-transformed marker values.