(A) | ||||||
---|---|---|---|---|---|---|

Genotype | Controls (n = 157) | RCC (n = 123) | Odds ratio (95% confidence intervals) | |||

Codon 62 | ||||||

C/C | 86 (54.8%) | 51 (41.5%) | 1.00 (reference) | |||

C/T | 63 (40.1%) | 57 (46.3%) | 1.53 (0.93-2.50) | |||

T/T | 8 (5.1%) | 15 (12.2%) | 3.16 (1.29-7.73) | |||

P = 0.025 | ||||||

Codon 72 | ||||||

G/G | 130 (82.8%) | 106 (86.2%) | 1.00 (reference) | |||

G/T | 25 (15.9%) | 16 (13.0%) | 0.78 (0.40-1.53) | |||

T/T | 2 (1.3%) | 1 (0.8%) | 0.61 (0.06-6.03) | |||

Codon 158 | ||||||

G/G | 85 (54.1%) | 59 (48.0%) | 1.00 (reference) | |||

G/A | 61 (38.8%) | 54 (43.9%) | 1.28 (0.78-2.09) | |||

A/A | 11 (7.0%) | 10 (8.1%) | 1.31 (0.52-3.30) | |||

(B) | ||||||

Allele | Controls (n = 314) | RCC (n = 246) | ||||

Codon 62 | ||||||

C | 235 (74.8%) | 159 (64.6%) | ||||

T | 79 (25.2%) | 87 (35.4%) | ||||

P = 0.011 | ||||||

Codon 72 | ||||||

G | 285 (90.8%) | 228 (92.7%) | ||||

T | 29 (9.2%) | 18 (7.3%) | ||||

Codon 158 | ||||||

G | 231 (73.6%) | 172 (69.9%) | ||||

A | 83 (26.4%) | 74 (30.1%) |

NOTE:

*P*values reflect χ^{2}test.