Table 1.

Genes and SNPs evaluated

GeneNameLocationSNP/amino acid changedbSNP rs no.
IFNGR2IFN-γ receptor 221q22.11Ex2−16A>G/Q64Rrs9808753
Ex7−128C>T (3′-UTR)rs1059293
IL10RAInterleukin 10 receptor antagonist11q23Ex7+241G>A (R351G)rs2229113
IL10Interleukin 101q31-32−3584T>Ars1800890
−1116A>Grs1800896
−853C>Trs1800871
−626C>Ars1800872
IL12AInterleukin 12, α subunit3p12-q13.2Ex7+277G>A (3′-UTR)rs568408
IL13Interleukin 135q31−1069C>Trs1800925
Ex4−98G>A/Q144Rrs20541
IL1AInterleukin 1, α subunit2q14Ex1+12C>Trs1800587
IL1BInterleukin 1, β subunit2q14−1060C>Trs16944
IL1RNInterleukin 1 receptor antagonist2q14.2IVS6+59A>Trs454078
IL2Interleukin 24q26-q27IVS1−100T>Grs2069762
IL4RInterleukin 4 receptor16p11.2-12.1Ex10+608T>C/S503Prs1805015
Ex11+828A>G/Q576Rrs1801275
IL4Interleukin 45q31.1−1098T>Grs2243248
−588C>Trs2243250
Ex1−168C>Trs2070874
IL6Interleukin 67p21−600G>Ars1800797
−236G>Crs1800795
LTALymphotoxin α6p21.3Ex1+49C>Ars2239704
252A>Grs909253
TGFB1Transforming growth factor, β119q13.2−509C>Trs1800469
Ex1−327T>C/L10Prs1982073
Ex1−282G>C/P25Rrs1800471
Ex5−73C>T/T263Irs1800472
TNFRSF10ATumor necrosis factor receptor8p21Ex4−4G>C/R209Trs4871857
superfamily, member 10a
(TRAIL receptor)
TNFTumor necrosis factor α6p21.3−1042C>Ars1800630
−1036C>Trs1799724
−487G>Ars1800629
−238G>Ars361525
  • Abbreviations: UTR, untranslated region; TRAIL, TNF-related apoptosis-inducing ligand.