Table 2.

RR and 95% CI values for the association between BMI and prostate cancer incidence (CPS-II Nutrition Cohort, 1992-2003)


BMI in 1992 (kg/m2)
Ptrend
<25.025.0 to <27.527.5 to <30.030.0 to <35.0≥35.0
All cases
    No. of cases1,9351,74292055699
    Person-years171,338153,58587,65257,50811,344
    RR (95% CI)*1.00 (ref)1.02 (0.95-1.08)0.95 (0.88-1.03)0.89 (0.81-0.98)0.83 (0.68-1.02)0.003
    RR (95% CI)1.00 (ref)1.02 (0.96-1.09)0.98 (0.90-1.06)0.94 (0.85-1.04)0.91 (0.75-1.12)0.14
Nonmetastatic low grade
    No. of cases1,5441,40970041273
    Person-years171,338153,58587,65257,50811,344
    RR (95% CI)*1.00 (ref)1.02 (0.95-1.09)0.89 (0.81-0.97)0.81 (0.72-0.90)0.75 (0.59-0.94)<0.0001
    RR (95% CI)1.00 (ref)1.03 (0.96-1.10)0.92 (0.84-1.01)0.86 (0.77-0.97)0.84 (0.66-1.06)0.002
Nonmetastatic high grade
    No. of cases239180140103
    Person-years171,338153,58587,65268,852
    RR (95% CI)*1.00 (ref)0.87 (0.71-1.05)1.21 (0.98-1.49)1.17 (0.93-1.48)§0.06
    RR (95% CI)1.00 (ref)0.87 (0.72-1.06)1.23 (1.00-1.53)1.22 (0.96-1.55)§0.03
Stage D or fatal cases
    No. of cases921044646
    Person-years171,338153,58587,65268,852
    RR (95% CI)*1.00 (ref)1.40 (1.06-1.86)1.14 (0.80-1.63)1.57 (1.09-2.24)§0.03
    RR (95% CI)1.00 (ref)1.41 (1.06-1.87)1.14 (0.79-1.63)1.54 (1.06-2.23)§0.05
  • * Adjusted for age at interview.

  • Adjusted for age at interview, race, education, family history of prostate cancer, total calorie intake, smoking status, history of PSA testing, history of diabetes, and physical activity.

  • One hundred and sixty-four nonmetastatic low-grade cases excluded due to missing Gleason score information.

  • § This value is for BMI 30 to <35 and BMI ≥35 groups combined.