Table 2.

ORs and 95% CIs for lifetime physical activity in relation to risk of breast carcinoma in situ

Type of strenuous activityControls (n = 7,630)In situ cases (n = 1,689)OR (95% CI)*OR (95% CI)
Recreational
    0 h/wk9511881.00 (Reference)1.00 (Reference)
    0.1-3 h/wk5,4031,2101.12 (0.94-1.32)1.01 (0.85-1.21)
    3.1-6 h/wk8151961.19 (0.95-1.49)1.06 (0.84-1.34)
    >6 h/wk461951.03 (0.78-1.35)0.93 (0.70-1.24)
        P for trend0.540.87
    0 MET-h/wk9511881.00 (Reference)1.00 (Reference)
    0.1-17.5 MET-h/wk5,2691,1981.13 (0.96-1.34)1.03 (0.86-1.23)
    17.6-35 MET-h/wk8842001.12 (0.89-1.39)1.00 (0.79-1.26)
    >35 MET-h/wk5261030.97 (0.75-1.27)0.87 (0.66-1.15)
        P for trend0.840.32
Occupational
    0 h/wk3,3048141.00 (Reference)1.00 (Reference)
    0.1-12.5 h/wk1,9653990.81 (0.71-0.93)0.87 (0.76-1.00)
    12.6-25 h/wk6481250.77 (0.62-0.95)0.85 (0.69-1.06)
    >25 h/wk409930.88 (0.69-1.12)0.93 (0.73-1.19)
        P for trend0.010.12
    0 MET-h/wk3,3048141.00 (Reference)1.00 (Reference)
    0.1-50 MET-h/wk1,9183910.82 (0.71-0.93)0.87 (0.76-1.00)
    50.1-100 MET-h/wk6401230.77 (0.62-0.94)0.85 (0.69-1.06)
    >100 MET-h/wk4641030.86 (0.69-1.08)0.93 (0.73-1.17)
        P for trend0.010.12
Total activity
    0 h/wk381871.00 (Reference)1.00 (Reference)
    0.1-15 h/wk4,8971,1300.98 (0.77-1.25)0.92 (0.72-1.19)
    15.1-30 h/wk7601510.83 (0.62-1.12)0.83 (0.62-1.13)
    >30 h/wk288630.89 (0.62-1.28)0.86 (0.59-1.24)
        P for trend0.140.22
    0 MET-h/wk381871.00 (Reference)1.00 (Reference)
    0.1-62.5 MET-h/wk4,7661,1070.99 (0.77-1.26)0.93 (0.72-1.20)
    62.6-125 MET-h/wk8261630.83 (0.62-1.10)0.82 (0.61-1.10)
    >125 MET-h/wk353740.85 (0.60-1.20)0.82 (0.57-1.17)
        P for trend0.060.10
  • NOTE: Lifetime activity defined as from age 14 to 1 yr before the reference date.

  • * ORs are adjusted for age and state.

  • ORs are adjusted for age, state, mammography, menopausal status, family history of breast cancer, parity, age at first birth, age at menarche, age at menopause, postmenopausal hormone use, education, alcohol, BMI, and weight change since age 18.

  • Total activity is sum of subject's recreational and occupational activity.