Table 2.

Adjusted mean (95% CI) percent and absolute mammographic densities by quartiles of IGF-I and IGFBP-3 concentrations and IGF-I/IGFBP-3 molar ratio among 977 postmenopausal Norwegian women

Adjusted mean* (95% CI) percent mammographic density (%)Adjusted mean* (95% CI) absolute mammographic density (cm2)
IGF-I (N = 977)
    Q17.50 (6.56-8.56)10.71 (9.22-12.44)
    Q28.09 (7.11-9.21)11.58 (10.01-13.38)
    Q38.94 (7.84-10.18)12.80 (11.05-14.83)
    Q49.07 (7.97-10.32)13.08 (11.31-15.13)
    Ptrend0.020.04
IGFBP-3 (n = 975)
    Q18.46 (7.42-9.65)12.12 (10.45-14.06)
    Q27.93 (6.96-9.02)11.45 (9.89-13.25)
    Q38.67 (7.60-9.89)12.25 (10.56-14.21)
    Q48.54 (7.50-9.73)12.32 (10.64-14.26)
    Ptrend0.690.73
IGF-I/IGFBP-3 molar ratio (n = 975)
    Q17.37 (6.47-8.41)10.67 (9.21-12.38)
    Q28.16 (7.17-9.29)11.65 (10.06-13.48)
    Q39.40 (8.25-10.72)13.47 (11.62-15.61)
    Q48.77 (7.72-9.96)12.52 (10.84-14.45)
    Ptrend0.020.06
  • NOTE: Analyses are adjusted for age at screening, number of children, age at menopause, BMI, and postmenopausal hormone therapy use (never, past, and current). IGFBP-3 concentration and IGF-I/IGFBP-3 ratio are missing for two women.

  • * Reported means are back-transformed from log-transformed estimated means.