Table 1.

Baseline characteristics of ovarian cancer cases and matched controls

Premenopausal women
Postmenopausal women
Cases (n = 56)Controls (n = 109)pdiff*Cases (n = 136)Controls (n = 237)pdiff*
Age at blood donation (y)46.1 (36.1-54.1)45.8 (37.4-53.0)60.9 (51.9-70.6)60.9 (52.1-71.5)
Age at diagnosis (y)48.9 (39.0-60.0)63.8 (54.0-74.0)
Time since blood donation (y)3.3 (0.2-7.6)3.4 (0.6-7.6)
Height (cm)161.1 (152.0-172.0)161.0 (151.5-172.0)0.87159.4 (148.5-169.5)160.5 (149.0-171.5)0.03
Weight (kg)68.6 (50.5-95.0)64.3 (50.0-85.3)0.0270.9 (52.3-94.0)70.2 (53.0-93.0)0.67
BMI26.5 (20.7-35.8)24.8 (19.2-33.4)0.0227.9 (21.8-35.9)27.3 (20.2-37.2)0.18
Waist (cm)82.0 (68.0-102.0)79.1 (66.0-96.0)0.0886.5 (69.0-106.0)86.3 (70.0-108.3)0.70
Waist-to-hip ratio0.80 (0.70-0.95)0.79 (0.71-0.91)0.190.81 (0.72-0.92)0.83 (0.71-0.95)0.10
Age at menarche (y)12.5 (11.0-15.0)12.8 (11.0-16.0)0.2113.7 (11.0-17.0)13.4 (11.0-16.0)0.13
Parous76.890.80.0181.686.10.21
Age at first full-term pregnancy (y)25.3 (20.0-32.0)25.2 (20.0-31.0)0.9725.4 (19.0-32.0)24.8 (18.0-32.0)0.08
No. full-term pregnancy1.9 (1.0-3.0)2.1 (1.0-4.0)0.182.3 (1.0-5.0)2.5 (1.0-5.0)0.07
Previous OC use58.963.30.5328.732.90.35
OC use duration (y)4.4 (1.0-15.0)5.9 (1.0-30.0)0.145.9 (1.0-30.0)9.5 (1.0-30.0)0.11
Previous HRT use21.321.10.94
Age at menopause (y)50.1 (43.0-56.0)49.4 (40.0-56.0)0.17
Smoking status
    Never57.151.40.7659.662.50.49
    Former21.425.722.116.9
    Current21.422.918.419.8
Ever had fertility problems5.44.60.780.72.10.34
Ever breast-feeding62.568.80.3074.373.00.86
  • NOTE: Mean (5th-95th percentiles) or percentages.

    Abbreviations: OC, oral contraceptive; HRT, hormone replacement therapy.

  • * Paired t test.

  • χ2 test.