Table 4.

Age-adjusted risk of subsequent breast events among women diagnosed with DCIS stratified by radiation status

Breast densityAny invasive cancer (n = 133)*
Ipsilateral invasive cancer (n = 83)
Contralateral invasive cancer (n = 5 2)
Contralateral DCIS (n = 30)
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
No radiation (n = 1,536)
Low (BI-RADS 1, 2)1.001.001.001.00
High (BI-RADS 3, 4)1.2 (0.7-2.0)0.9 (0.5-1.7)2.7 (1.0-7.5)1.6 (0.5-4.7)
Radiation (n = 1,354)
Low (BI-RADS 1, 2)1.001.001.001.00
High (BI-RADS 3, 4)1.7 (0.8-3.3)1.1 (0.5-2.5)3.6 (1.1-11.3)0.8 (0.1-4.4)
  • * Includes two patients with bilateral invasive cancer events.