Table 2.

Effects of aerobic and resistance exercise during breast cancer chemotherapy on patient-rated outcomes at 6-month follow-up

Baseline M (SD)Follow-up M (SD)Mean change M (95% CI)Unadjusted group differences in mean change: M (95% CI); PAdjusted group differences in mean change: M (95% CI); P
FACT-An
    UC135.3 (28.1)152.4 (26.4)+18.2 (11.5-24.9)RET vs UC: +2.3 (−6.9-11.5); P = 0.620+2.7 (−6.6-12.1); P = 0.566
    RET132.2 (23.5)152.9 (26.0)+20.5 (14.2-26.8)AET vs UC: +1.9 (−7.4-11.3); P = 0.686+2.9 (−6.6-12.4); P = 0.546
    AET135.7 (29.0)156.3 (24.0)+20.1 (13.6-26.6)RET vs AET: +0.4 (−8.6-9.4)−0.2 (−9.5-9.1)
Self-esteem
    UC34.1 (4.6)33.9 (5.6)−0.1 (−1.2-1.0)RET vs UC: +1.2 (−0.3-2.7); P = 0.119+1.6 (0.1-3.2); P = 0.032
    RET34.1 (4.2)35.2 (4.6)+1.1 (0.1-2.1)AET vs UC: +1.0 (−0.5-2.5); P = 0.201+1.0 (−0.5-2.5); P = 0.187
    AET34.0 (5.1)35.0 (4.7)+0.9 (−0.1-2.0)RET vs AET: +0.2 (−1.3-1.7)+0.6 (−0.8-2.1)
Fatigue
    UC34.6 (11.1)41.5 (9.8)+7.0 (4.1-10.0)RET vs UC: −0.6 (−4.6-3.4); P = 0.754−0.1 (−4.1-3.9); P = 0.966
    RET34.3 (10.1)40.8 (10.5)+6.4 (3.7-9.1)AET vs UC: −0.4 (−4.5-3.6); P = 0.831+0.6 (−3.5-4.6); P = 0.779
    AET35.3 (12.1)42.1 (10.5)+6.6 (3.8-9.4)RET vs AET: −0.2 (−4.1-3.7)−0.7 (−4.6-3.3)
Anxiety
    UC42.0 (13.7)37.4 (12.0)−5.3 (−8.6 to −1.9)RET vs UC: −1.3 (3.3 to −5.8); P = 0.582−2.5 (2.1 to −7.1); P = 0.279
    RET42.0 (12.0)35.5 (13.0)−6.5 (−9.7 to −3.4)AET vs UC: −3.7 (0.9 to −8.4); P = 0.113−4.7 (−0.0 to −9.3); P = 0.049
    AET40.9 (13.3)32.2 (11.2)−9.0 (−12.2 to −5.8)RET vs AET: +2.5 (2.0 to −6.9)+2.1 (2.4 to −6.7)
Depression
    UC13.9 (9.7)10.2 (9.5)−4.0 (−6.6 to −1.3)RET vs UC: −0.2 (3.5 to −3.8); P = 0.932−1.3 (2.3 to −4.8); P = 0.493
    RET13.8 (10.1)9.6 (10.4)−4.1 (−6.6 to −1.7)AET vs UC: −1.6 (2.1 to −5.3); P = 0.395−2.7 (1.0 to −6.3); P = 0.154
    AET12.8 (9.8)7.2 (7.5)−5.6 (−8.2 to −3.0)RET vs AET: +1.4 (5.0 to −2.1)+1.4 (5.0 to −2.2)
  • NOTE: M (SD) at 6-month follow-up is based on available data. Mean change is based on 6-month follow-up score minus baseline score but may not precisely reflect this difference given that mean change is estimated based on mixed model analysis. Adjusted group difference in mean change was adjusted for baseline value of the outcome, age, marital status, employment status, disease stage, chemotherapy protocol, baseline exercise status, and smoking status. P values are presented only for hypothesized comparisons.