Table 6.

Physical state of HPV16 as related to type-specific outcomes

Type-specific outcomeEpisomal (%)Integrated (%)Mixed* (%)TotalArea under ROC curve (95% CI)
Persistent infection40 (54.1)3 (4.1)31 (41.9)74 (100.0)0.390 (0.316-0.463)
Infection cleared16 (32.7)2 (4.1)31 (63.3)49 (100.0)0.562 (0.482-0.642)
One positive real-time PCR test3 (15.8)3 (15.8)13 (68.4)19 (100.0)NA
Fluctuator3 (75.0)0 (0.0)1 (25.0)4 (100.0)0.329 (0.081-0.576)
Type changed (single)5 (31.3)2 (12.5)9 (56.3)16 (100.0)0.557 (0.433-0.680)
Type changed (multiple)4 (44.4)1 (11.1)4 (44.4)9 (100.0)0.485 (0.308-0.661)
Total711189171
Comparison of areas under ROC curvesP = 0.078
  • Abbreviations: ROC, receiving operating curve; NA, not applicable.

  • * Episomal and integrated form.

  • Calculated using the dichotomous variable integration (yes/no).

  • Calculated using STATA/SE software (ROC curve options).