Table 2.

Univariate and multivariate Cox regression analysis

Telomere lengthNo. patients (EA/total)Unadjusted
Age adjusted
Adjusted for other risk factors*
HR (95% CI)PHR (95% CI)PHR (95% CI)P
Categorical variable
    First quartile (longest)4/751.001.001.00
    Second quartile9/752.57 (0.72-10.78)0.172.40 (0.62-9.32)0.212.39 (0.61-9.34)0.21
    Third quartile10/753.27 (0.93-12.34)0.072.99 (0.82-10.98)0.103.49 (0.94-12.87)0.06
    Fourth quartile (shortest)15/754.59 (1.40-17.32)0.023.99 (1.11-14.33)0.034.66 (1.28-16.93)0.02
Continuous variable
    Fourth vs first quartile38/3003.93 (1.59-9.70)0.0033.45 (1.35-8.78)0.0094.18 (1.60-10.94)0.004
  • Abbreviation: EA, esophageal adenocarcinoma.

  • * Age, gender, NSAID use, smoking, and WHR.

  • Median of fourth quartile versus median of first quartile.