Table 5.

Sensitivity, specificity, positive predictive value, and negative predictive value of combinations of factors for detection of atrophic gastritis, corpus atrophic gastritis, and intestinal metaplasia in Costa Rican dyspeptic patients

FactorsSe [% (95% CI)]Sp [% (95% CI)]PPV [% (95% CI)]NPV [% (95% CI)]
Detection of atrophic gastritis
    L-PG, CagA-ab63.8 (50.6-77.0)81.2 (75.0-87.5)54.4 (41.8-67.0)86.5 (80.7-92.2)
    VL-PG, CagA-ab48.3 (34.6-62.0)94.6 (90.8-98.3)75.7 (60.5-90.9)83.9 (78.3-89.4)
Detection of corpus atrophic gastritis
    L-PG, CagA-ab80.7 (65.1-96.2)77.6 (71.5-83.8)36.8 (24.6-49.0)96.1 (92.8-99.5)
    VL-PG, CagA-ab74.2 (57.2-91.2)92.7 (88.8-96.7)62.2 (45.2-79.1)95.7 (92.5-98.9)
Detection of intestinal metaplasia
    L-PG, CagA-ab, IL+3954T, IL*2/221.7 (2.7-40.8)96.7 (93.9-99.6)45.5 (11.5-79.4)90.8 (86.5-95.1)
    VL-PG, CagA-ab, IL+3954T, IL*2/217.4 (0.0-35.1)99.5 (98.1-100)80.0 (34.9-100)90.6 (86.3-94.9)