Table 3.

Sensitivity, specificity, positive predictive value and negative predictive value for detection of atrophic gastritis, corpus atrophic gastritis and intestinal metaplasia in Costa Rican dyspeptic patients

FactorsSe [% (95% CI)]Sp [% (95% CI)]PPV [% (95% CI)]NPV [% (95% CI)]
Detection of atrophic gastritis
    L-PG77.6 (66.0-89.2)61.2 (53.5-69.0)41.3 (31.6-51.0)88.6 (82.3-94.9)
    VL-PG51.7 (38.0-65.4)81.2 (75.0-87.5)46.2 (35.8-62.6)82.7 (76.6-88.9)
    CagA-ab82.8 (72.2-93.3)51.5 (43.6-59.4)37.5 (28.7-46.3)89.5 (82.8-96.2)
Detection of corpus atrophic gastritis
    L-PG87.1 (73.7-100)57.3 (50.0-64.6)24.8 (16.2-33.3)96.5 (92.7-100)
    VL-PG77.4 (61.1-93.8)80.7 (74.9-86.6)39.3 (26.3-52.4)95.7 (92.2-99.1)
    CagA-ab90.3 (78.3-100)47.9 (40.6-55.2)21.9 (14.3-29.4)96.8 (92.8-100)
Detection of intestinal metaplasia
    VL-PG78.3 (59.2-97.3)78.5 (72.6-84.4)29.5 (17.2-41.8)96.9 (93.9-99.9)
    CagA-ab95.7 (85.1-100)47.0 (39.8-54.2)17.2 (10.3-24.1)99.0 (96.4-100)
    IL+3954T80.0 (60.0-100)48.9 (40.3-57.6)18.4 (9.7-27.1)94.4 (88.5-100)
    IL*2/240.0 (16.0-64.0)87.1 (81.1-93.0)30.8 (11.1-50.4)91.0 (85.7-96.2)
  • Abbreviations: Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.