Table 4.

Relation between gender of offspring and maternal risk of ovarian cancer in uniparous, biparous, triparous, and all women

Gender of offspringCases/controlsCrude OR (95% CI)Adjusted OR* (95% CI)Birth year <1935, adjusted OR* (95% CI)
Among uniparous women (n = 10,724)
    Boy1,058/4,4780.97 (0.89-1.07)0.97 (0.88-1.07)0.94 (0.82-1.08)
    Girl1,013/4,1751.00 (reference)1.00 (reference)1.00 (reference)
Among biparous women (n = 19,811)
    1st child
        Boy1,680/8,5220.96 (0.89-1.04)0.96 (0.89-1.04)0.92 (0.82-1.02)
        Girl1,633/7,9761.00 (reference)1.00 (reference)1.00 (reference)
    2nd child
        Boy1,664/8,4890.95 (0.88-1.03)0.96 (0.89-1.03)0.92 (0.82-1.03)
        Girl1,649/8,0091.00 (reference)1.00 (reference)1.00 (reference)
    1st child/2nd child
        Boy/boy826/4,2000.91 (0.82-1.02)0.91 (0.82-1.02)0.84 (0.71-0.98)
        Boy/girl854/4,3220.92 (0.82-1.02)0.91 (0.82-1.01)0.87 (0.74-1.02)
        Girl/boy838/4,2890.91 (0.82-1.01)0.90 (0.81-1.01)0.87 (0.75-1.02)
        Girl/girl795/3,6871.00 (reference)1.00 (reference)1.00 (reference)
Among triparous women (n = 9,848)
    1st child
        Boy722/4,4030.95 (0.85-1.06)0.95 (0.85-1.06)0.93 (0.79-1.10)
        Girl696/4,0271.00 (reference)1.00 (reference)1.00 (reference)
    2nd child
        Boy703/4,4230.89 (0.80-0.99)0.89 (0.80-1.00)0.83 (0.70-0.98)
        Girl715/4,0071.00 (reference)1.00 (reference)1.00 (reference)
    3rd child
        Boy727/4,4310.95 (0.85-1.06)0.94 (0.84-1.06)0.98 (0.83-1.16)
        Girl691/3,9991.00 (reference)1.00 (reference)1.00 (reference)
    Three boys196/1,2760.81 (0.65-1.01)0.81 (0.65-1.00)0.72 (0.52-0.98)
    Two boys and one girl526/3,2490.86 (0.71-1.03)0.85 (0.71-1.02)0.76 (0.58-0.98)
    One boy and two girls512/2,9310.93 (0.77-1.11)0.92 (0.76-1.10)0.77 (0.59-1.01)
    Three girls184/9741.00 (reference)1.00 (reference)1.00 (reference)
All women (n = 45,065)
    All boys2,103/10,0070.93 (0.87-0.99)0.93 (0.87-0.99)0.88 (0.80-0.97)
    Mixed boys and girls3,297/18,8150.77 (0.73-0.82)0.89 (0.83-0.95)0.89 (0.80-0.98)
    All girls2,007/8,8361.00 (reference)1.00 (reference)1.00 (reference)
  • * Data are adjusted for age at diagnosis or enrollment, age at first childbirth, education level closest to age 40, and area of residence closest to age 40. For biparous and triparous women, data are further adjusted for age at last birth with the previous covariates. For all women, data are further adjusted for parity.