Table 2.

Race-specific and age- and sex-adjusted means and percentages of baseline risk factors by presence of PCSK9 variants, ARIC, 1987-89

Blacks
Whites
PCSK9142X or PCSK9679X (n = 85)Neither variant (n = 3,392)P for differencePCSK946L (n = 314)Neither variant (n = 9,459)P for difference
Means
    LDL cholesterol (mg/dL)98.8138.9<0.0001117.7138.3<0.0001
    Total cholesterol (mg/dL)172.2215.7<0.0001195.9215.4<0.0001
    Triglycerides (mg/dL)95.8111.40.06140.0137.10.59
    BMI (kg/m2)29.329.60.6926.927.10.69
    Pack-years of smoking206.5240.50.41393.6341.30.03
    Ethanol intake (g/wk)19.033.00.1840.246.10.26
    Sports activity index (range, 0-5)2.082.160.322.472.530.18
Prevalences
    High school graduate (%)56.959.10.6782.382.80.83
    Diabetes (%)12.716.50.358.58.60.96
    Current smoking (%)27.929.70.7225.224.20.68
    Current HRT use, women (%)22.918.90.4530.123.60.05
  • Abbreviations: BMI, body mass index; HRT, hormone replacement therapy.