Table 1.

Adjusted HRs (95% CI) of cancer by LDL and total cholesterol quartiles in blacks and whites, ARIC, 1987-2000

Quartile 4Quartile 3Quartile 2Quartile 1P trend
Blacks
    LDL cholesterol(n = 834)(n = 835)(n = 835)(n = 834)
        Range (mg/dL)>164135-164108-135<108
        Cases10811310592
        Model 1*1.01.11 (0.86-1.45)1.06 (0.81-1.39)1.01 (0.77-1.34)0.86
        Model 21.01.16 (0.89-1.54)1.06 (0.80-1.40)1.05 (0.78-1.40)0.73
    Total cholesterol(n = 841)(n = 833)(n = 844)(n = 842)
        Range (mg/dL)≥242212-241184-211≤183
        Cases103111104104
        Model 1*1.01.13 (0.87-1.48)1.10 (0.83-1.44)1.13 (0.86-1.49)0.79
        Model 21.01.16 (0.88-1.54)1.19 (0.89-1.58)1.21 (0.91-1.61)0.56
Whites
    LDL cholesterol(n = 2,400)(n = 2,401)(n = 2,401)(n = 2,400)
        Range (mg/dL)>161135-161112-135<112
        Cases333321297314
        Model 1*1.01.01 (0.87-1.18)0.97 (0.83-1.14)1.12 (0.96-1.31)0.30
        Model 21.01.01 (0.86-1.18)1.00 (0.85-1.17)1.16 (0.99-1.36)0.20
    Total cholesterol(n = 2,430)(n = 2,415)(n = 2,459)(n = 2,456)
        Range (mg/dL)≥239213-238188-212≤187
        Cases335316329303
        Model 1*1.01.00 (0.86-1.17)1.06 (0.91-1.23)1.06 (0.91-1.24)0.80
        Model 21.01.03 (0.88-1.20)1.06 (0.91-1.25)1.09 (0.93-1.29)0.74
  • * Adjusted for age (continuous) and sex.

  • Adjusted for age (continuous), body mass index (continuous), triglycerides (continuous), diabetes (yes, no), smoking status (current smoker, nonsmoker), pack-years (continuous), ethanol intake (continuous), sport index (continuous), education (<high school graduate, ≥high school graduate), and sex and current hormone replacement therapy (male and female with no hormone replacement therapy, female with hormone replacement therapy).