Table 2.

Family history of selected cancer sites and risk of lung cancer among nonsmokers

CasesPerson-yearsRR* (95% CI)
Any cancers46147.501.06 (0.76-1.48)
    Parents3086.050.97 (0.65-1.45)
    Siblings2585.261.70 (1.10-2.63)
Tobacco-related cancers§1867.571.13 (0.69-1.85)
    Parents1240.651.02 (0.56-1.84)
    Siblings834.571.81 (0.88-3.72)
Lung724.580.89 (0.42-1.91)
    Parents410.360.69 (0.25-1.86)
    Siblings314.221.46 (0.46-4.59)
Esophagus829.481.80 (0.88-3.67)
    Parents724.531.96 (0.92-4.19)
    Siblings14.950.97 (0.14-6.97)
Stomach1437.061.34 (0.77-2.33)
    Parents717.010.97 (0.45-2.08)
    Siblings720.052.16 (1.01-4.65)
Colorectum931.812.38 (1.21-4.70)
    Parents616.212.33 (1.02-5.28)
    Siblings315.602.63 (0.84-8.31)
Liver718.921.20 (0.56-2.57)
    Parents410.041.13 (0.42-3.05)
    Siblings38.871.32 (0.42-4.15)
Pancreas313.511.93 (0.62-6.07)
    Parents15.750.95 (0.13-6.83)
    Siblings27.764.19 (1.04-16.95)
Breast510.051.54 (0.63-3.76)
    Parents10.210.67 (0.09-4.77)
    Siblings49.852.45 (0.90-6.65)
  • * Adjusted for age, passive smoking, number of siblings, and number of children.

  • Adjusted for age and passive smoking.

  • Adjusted for age, passive smoking, and number of siblings.

  • § Tobacco related cancers including cancer of the lung, oral cavity, pharynx, esophagus, pancreas, bladder, and kidney.