Table 1.

SIR of cancer for the offspring of women who experienced death of father or mother during pregnancy

Cancer siteAge at cancer diagnosis
Any age
<15 y
nSIR* (95% CI)nSIR* (95% CI)
Leukemia441.49 (1.11-2.01)321.51 (1.07-2.14)
    Acute lymphoblastic leukemia311.69 (1.19-2.42)251.58 (1.06-2.34)
Nervous system340.97 (0.70-1.36)150.82 (0.49-1.36)
    Brain301.04 (0.73-1.49)140.93 (0.55-1.57)
Melanoma230.91 (0.60-1.37)
Hodgkin's disease201.71 (1.10-2.66)21.39 (0.35-5.61)
Non-Hodgkin's lymphoma151.33 (0.80-2.21)61.26 (0.56-2.81)
Testis131.80 (1.04-3.10)
    Embryonal carcinoma43.54 (1.32-9.48)
    Seminoma30.48 (0.15-1.48)
    Teratoma30.94 (0.30-2.93)
Breast120.77 (0.44-1.36)
Colon101.12 (0.60-2.10)43.95 (1.46-10.7)
    Appendix (carcinoid)71.34 (0.63-2.82)44.13 (1.52-11.2)
  • Abbreviation: 95% CI, 95% confidence interval.

  • * Adjusted for age, sex, period, socioeconomic index, region, and age of the mother at delivery.