Table 1.

HPV infections present before LEEP, persistent after LEEP, cleared after LEEP, and reappeared during the follow-up period, by HPV genotype, carcinogenicity, and phylogenetic species

Present before LEEP, nPersistent after LEEP, n (%)Cleared* after LEEP, nReappeared during follow-up, n (%)
Overall HPV infection1,130231 (20.4)82064 (7.8)
Carcinogenic HPV839149 (17.8)63043 (6.8)
Noncarcinogenic HPV29182 (28.2)19021 (11.1)
α9/α11567100 (17.6)42832 (7.5)
    1626358 (22.1)19511 (5.6)
    31749 (12.2)563 (5.4)
    33453 (6.7)382 (5.3)
    35383 (7.9)314 (12.9)
    527512 (16.0)578 (14.0)
    584411 (25.0)283 (10.7)
    67121 (8.3)100 (0)
    73163 (18.8)131 (7.7)
    P0.0520.4
α719535 (17.9)14610 (6.8)
    18577 (12.3)463 (6.5)
    39404 (10.0)331 (3.0)
    45308 (26.7)192 (10.5)
    59297 (24.1)200 (0)
    68245 (20.8)173 (17.6)
    70154 (26.7)111 (9.1)
    P0.20.3
α311547 (40.9)6214 (22.6)
    61187 (38.9)105 (50.0)
    622112 (57.1)71 (14.3)
    7283 (37.5)52 (40.0)
    8184 (50.0)40 (0)
    83229 (40.9)132 (15.4)
    84186 (33.3)112 (18.2)
    89206 (30.0)122 (16.7)
    P0.70.4
α5/α616927 (16.0)1304 (3.1)
    516311 (17.5)471 (2.1)
    53295 (17.2)221 (4.5)
    56337 (21.2)240 (0)
    66244 (16.7)192 (10.5)
    82200 (0)180 (0)
    P0.20.4
α1/α8/α10/α138422 (26.2)544 (7.4)
    6121 (8.3)80 (0)
    1160 (0)50 (0)
    4060 (0)60 (0)
    42166 (37.5)81 (12.5)
    54309 (30.0)193 (15.8)
    55146 (42.9)80 (0)
    P0.10.8
  • NOTE: HPV types considered carcinogenic are in bold. P represents P value for the χ2 test for heterogeneity.

  • * Restricted to HPV infections in women with at least two study visits following the LEEP to assess reappearance (n = 79 infections excluded).

  • Only HPV73 is in the α11 species; the majority of this category represents HPV types in the α9 species.