Table 3.

Change in prostaglandin (geometric mean, pg/mg protein) concentrations in colon mucosa biopsies from baseline to 12 months

Exercisers
Controls
βintP*
Baseline geometric mean (95% CI)12-Month geometric mean (95% CI)EBaseline geometric mean (95% CI)12-Month geometric mean (95% CI)C
WomenN = 42N = 47
    Prostaglandin E26.49 (5.84-7.14)6.40 (5.04-7.77)−1.46.67 (6.40-6.94)6.58 (6.03-7.14)−1.3−0.0010.99
    Prostaglandin F6.53 (6.05-7.01)6.51 (5.60-7.42)−0.36.54 (6.34-6.74)6.57 (6.18-6.96)+0.5−0.050.69
MenN = 47N = 48
    Prostaglandin E26.14 (5.44-6.85)6.18 (4.81-7.58)+0.76.31 (6.01-6.62)6.42 (5.83-7.02)+1.7−0.070.74
    Prostaglandin F6.36 (5.87-6.85)6.47 (5.54-7.39)+1.76.43 (6.22-6.64)6.59 (6.19-6.98)+2.5−0.050.67
  • NOTE: 95% CI, 95% confidence interval; %ΔE, percentage change of geometric mean in exercisers; %ΔC, percentage change of geometric mean in controls; βint, regression coefficient for intervention effect.

  • * Intervention effect comparing exercisers to controls.