Table 2.

Pearson correlation coefficients for associations between baseline prostaglandin concentrations in sigmoid colon mucosal biopsies and participant characteristics at baseline

Total population (N = 184)
Women (N = 89)
Men (N = 95)
PGE2PGFPGE2PGFPGE2PGF
Age (y)−0.090.040.020.13−0.14−0.03
BMI (kg/m2)0.080.110.100.140.080.08
Body fat (%; DEXA)0.090.14*0.130.17−0.070.03
Steps/d (pedometer)−0.05−0.08−0.16−0.190.030.02
VO2 max (mL/kg/min)−0.04−0.08−0.005−0.040.02−0.04
Energy intake in prior month (kcal/d)0.020.03−0.060.010.110.07
Fiber intake in prior month (g/d)0.040.060.110.280.06−0.03
Alcohol (g)−0.10−0.08−0.09−0.09−0.09−0.05
Colon tissue measures
    PGE2 (pg/mg protein)n/a0.73*n/a0.73*n/a0.74*
    PGF (pg/mg protein)0.73*n/a0.73*n/a0.74*n/a
Serum measures
    Insulin (units/mL)0.020.007−0.09−0.040.130.07
    Glucose (mg/dL)−0.15*−0.13−0.17−0.09−0.10−0.14
    IGF-I (ng/mL)−0.07−0.03−0.07−0.01−0.020.01
    IGFBP-3 (ng/mL)0.050.04−0.07−0.090.150.19
    SHBG (ng/mL)0.070.010.08−0.04−0.18−0.09
    Testosterone (ng/dL)−0.09−0.060.060.03−0.020.05
    Free testosterone (pg/mL)−0.07−0.040.0020.060.070.12
  • Abbreviations: BMI, body mass index; DEXA, dual energy X-ray absorptiometry; IGF-I, insulin-like growth factor I; IGFBP-3, insulin-like growth factor binding protein-3; PGE2, prostaglandin E2; PGF, prostaglandin F; SHBG, sex hormone binding globulin; VO2 max, maximal oxygen consumption; n/a, not applicable.

  • * P < 0.05.