Table 2.

Results of SMR analyses for the BE cohort

Underlying cause of death (ICD-10 code)ObservedExpectedSMR (95% CI)
All causes (A00-R99, V01-Y89)246203.061.21* (1.06-1.37)
All causes (A00-R99, V01-Y89) excluding esophageal malignancy (C15)233201.271.16 (1.01-1.32)
Neoplastic mortality
    All neoplasms (C00-D48)5447.631.13 (0.85-1.48)
        All neoplasms excluding esophageal cancer (C00-C14, C16-D48)4145.840.89 (0.64-1.21)
        Malignant neoplasm of esophagus (C15)131.797.26 (3.87-12.42)
        Malignant neoplasm of stomach (C16)32.711.11 (0.23-3.24)
        Malignant neoplasm of trachea, bronchus, and lung (C33-C34)1412.361.13 (0.62-1.90)
        Malignant neoplasm of colon, rectosigmoid junction, and anus (C18-C21)25.090.39 (0.05-1.42)
Nonneoplastic mortality
    Diseases of the circulatory system (I00-I99)10189.401.13 (0.92-1.37)
        Acute myocardial infarction (I21-I22)3429.591.15 (0.80-1.61)
        Ischemic heart disease excluding myocardial infarction (I23-I25)2520.501.22 (0.79-1.80)
        Cerebrovascular disease (I60-I69)2223.730.93 (0.58-1.40)
    Diseases of the respiratory system (J00-J99)4033.271.20 (0.86-1.64)
    Diseases of the digestive system (K00-K93)146.922.03 (1.11-3.40)
  • NOTE: 95% CIs are Poisson exact. The underlying causes of death and ICD-10 codes for individuals only included in the “All-cause” categories of analysis include septicemia (A412), aplastic anemia (D619), diabetes mellitus (E149; n = 2), mental and behavioral disorders (F03, n = 3; F102), diseases of the nervous system (G20, G309, G409), diseases of the musculoskeletal system and connective tissue (M009, n = 2; M259, M809), diseases of the genitourinary system (N179, N19, N390; n = 2), senility (R54, n = 7), motor vehicle accident, traffic (V892), fall on and from stairs and steps (W100, n = 2), accidental alcohol poisoning (X450, n = 2), exposure to unspecified factor causing injury (X598, X599), external cause, undetermined intent (Y120, Y219), surgical procedure (Y833, Y839). These deaths were not analyzed in a specific category due to limited numbers or irrelevant causes (i.e., R54, senility).

  • * Twice, one-sided P < 0.01.

  • Twice, one-sided P < 0.05.

  • Twice, one-sided P < 0.001.