Table 3.

Association of physical activity tertiles with estradiol and testosterone within menopausal transition categories

Physical activity tertilesTop (≥1,454 kcal/wk)Middle (644-1,449 kcal/wk)Lowest (0-643 kcal/wk)
Estradiol (pg/mL), mean (95% confidence interval)
    Postmenopause14.6 (11.0, 19.3)15.7 (10.7, 23.0)16.3 (11.8, 22.6)
    Late transmenopause*24.6 (17.8, 33.9)10.6 (24.4, 38.5)37.9 (29.4, 48.8)
    Early transmenopause37.6 (29.6, 47.8)34.8 (29.3, 41.4)34.7 (30.3, 39.7)
    Late premenopause34.8 (30.4, 39.8)44.4 (38.1, 51.2)36.5 (31.5, 42.3)
    Premenopause36.4 (33.0, 40.2)37.8 (34.4, 41.5)34.2 (31.5, 37.2)
Testosterone (ng/dL), mean (95% confidence interval)
    Postmenopause10.7 (7.4, 15.5)12.5 (8.8, 17.6)12.5 (8.9, 17.6)
    Late transmenopause10.9 (7.8, 15.2)13.5 (10.6, 17.2)16.0 (13.7, 18.6)
    Early transmenopause10.8 (8.1, 14.3)10.4 (8.6, 12.5)10.5 (8.9, 12.4)
    Late premenopause10.2 (8.3, 12.6)11.1 (8.7, 14.2)12.4 (10.2, 15.1)
    Premenopause10.5 (9.1, 12.1)10.2 (9.0, 11.6)9.4 (8.3, 10.6)
  • NOTE: Geometric means and 95% confidence intervals from multiple regression models that included up to four assessments per participant and adjusted for time on study, age, smoking status, and ethnicity.

  • * P = 0.02, comparing highest to lowest tertiles; P = 0.07, middle to lowest tertiles; P = 0.05 in χ2 test for linear trend.

  • P = 0.01, comparing highest to lowest tertiles; P = 0.11, middle to lowest tertiles; P < 0.01, in χ2 test for linear trend.