Table 3.

Risk factors by diagnosis and familiality, n (%) or mean (SD)

Barrett's esophagus (n = 276)
Adenocarcinoma of esophagus and gastroesophageal junction (n = 137)
Familial (n = 17)Nonfamilial (n = 259)PFamilial (n = 13)Nonfamilial (n = 124)P
Smoking
    Ever smoke (yes/no)12 (70.6%)157 (60.9%)0.42410 (76.9%)99 (79.8%)0.729
    Heaviest packs per day1.29 (1.16)1.06 (1.10)0.4021.46 (1.13)1.37 (1.15)0.775
Coffee
    Drink coffee (yes/no)14 (82.4%)195 (75.3%)0.51111 (84.6%)99 (79.8%)0.999
    Average cups per day2.41 (1.77)2.27 (2.42)0.8181.85 (1.86)2.47 (2.83)0.438
Alcoholic drinks per week
    None3 (17.6%)53 (20.7%)3 (23.1%)17 (13.7%)
    Less than 1 drink per week7 (41.2%)126 (49.2%)5 (38.5%)59 (47.6%)
    1-5 drinks per week3 (17.6%)42 (16.4%)0.3162 (15.4%)27 (21.8%)0.796
    5-10 drinks per week1 (5.9%)22 (8.6%)2 (15.4%)11 (8.9%)
    More than 10 drinks per week3 (17.6%)13 (5.1%)1 (7.7%)10 (8.1%)
BMI (kg/m2)
    Current29.7 (6.5)29.0 (5.2)0.62823.1 (3.3)26.4 (5.0)0.019
    1 year ago29.9 (7.0)29.0 (5.4)0.51125.7 (4.9)28.8 (6.0)0.072
    5 years ago29.0 (6.4)28.4 (5.0)0.68226.4 (5.1)29.5 (5.8)0.070
    10 years ago27.3 (6.3)27.5 (5.0)0.89227.6 (4.0)28.5 (5.3)0.555
    20 years ago25.9 (4.2)25.9 (4.5)0.96427.3 (4.3)27.1 (4.6)0.895
  • NOTE: χ2 tests or t tests for differences by familial status.