Table 2.

LOH in DL specimens

ResultBRCA1 locus (BRCA1 carriers)
BRCA2 locus (BRCA2 carriers)
n = 46 (%)n = 39 (%)
Concordant
    Heterozygous15 (32.6)17 (43.6)
    LOH8 (17.4)7 (17.9)
Discordant
    Mixed LOH/heterozygous16 (34.7)10 (25.6)
    Loss of opposite alleles7 (15.2)5 (12.8)