Table 4.

Pathway comparison from skin lesion and nonlesion comparison restricted to female never-smokers

PathwayNo. genesFisher statistic permutation PKolmogorov-Smirnov permutation P
Signal transduction through IL-1 receptor120.003960.02551
Genbank accession no.Gene symbolGene description
NM_002228JUNv-jun sarcoma virus 17 oncogene homologue (avian)
NM_020529NFKBIANuclear factor of κ light polypeptide gene enhancer in B-cell inhibitor, α
NM_001315MAPK14Mitogen-activated protein kinase 14
NM_000576IL1BIL-1β
NM_000600IL6IL-6 (IFN-β2)
NM_004620TRAF6TNF receptor–associated factor 6
NM_000594TNFTNF (superfamily, member 2)
NM_000575IL1AIL-1α
NM_003998NFKB1Nuclear factor of κ light polypeptide gene enhancer in B cells 1 (p105)
NM_001278CHUKConserved helix-loop-helix ubiquitous kinase
NM_003188MAP3K7Mitogen-activated protein kinase kinase kinase 7
XM_042066MAP3K1Mitogen-activated protein kinase kinase kinase 1