Table 2.

Genes differentially down-regulated in the skin lesion versus nonlesion comparison

Genbank accession no.Gene symbolGene descriptionRatio of geometric mean (lesion/nonlesion)
NM_002089CXCL2Chemokine (C-X-C motif) ligand 20.037
NM_004591CCL20Chemokine (C-C motif) ligand 200.059
NM_000576IL1BIL-1β0.077
NM_019006ZA20D3Zinc finger, A20 domain containing 30.122
NM_000636SOD2Superoxide dismutase 2, mitochondrial0.112
NM_000610CD44CD44 antigen (homing function and Indian blood group system)0.112
NM_001001437CCL3Chemokine (C-C motif) ligand 30.091
NM_002852PTX3Pentraxin-related gene, rapidly induced by IL-1β0.083
NM_000594TNFTNF (superfamily, member 2)0.077
NM_000891KCNJ2Potassium inwardly rectifying channel, subfamily J, member 20.101
NM_003940USP13Ubiquitin-specific peptidase 130.158
NM_003965CCRL2Chemokine (C-C motif) receptor like 20.128
NM_003897IER3Immediate-early response 30.140
M10098SRP68Signal recognition particle 68 kDa0.118
NM_004566PFKFB36-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 30.147
NM_014887PFAAP5Phosphonoformate immuno-associated protein 50.170
M27830SOX18Sex-determining region Y-box 180.152
NM_005346HSPA1BHeat shock protein 1B, 70-kDa0.086
NM_007115TNFAIP6TNF-α-induced protein 60.115
NM_005066SFPQSplicing factor proline/glutamine rich (polypyrimidine tract–binding protein associated)0.189
NM_005751AKAP9A kinase (PRKA) anchor protein (yotiao) 90.198
NM_003414ZNF267Zinc finger protein 2670.181
AL049987MGC22265Hypothetical protein MGC222650.210
NM_006186NR4A2Nuclear receptor subfamily 4, group A, member 20.170
NM_002919RFX3Regulatory factor X, 3 (influences HLA class II expression)0.204
NM_001001723TMEM1Transmembrane protein 10.216
NM_004897MINPP1Multiple inositol polyphosphate histidine phosphatase, 10.228
NM_003143SSBP1ssDNA-binding protein 10.210
NM_018555ZNF331Zinc finger protein 3310.199
NM_002922RGS1Regulator of G-protein signaling 10.179
NM_002090CXCL3Chemokine (C-X-C motif) ligand 30.153
NM_002078GOLGA4Golgi autoantigen, golgin subfamily A, 40.234
NM_016166PIAS1Protein inhibitor of activated STAT 10.205
NM_014961RIPXRap2-interacting protein X0.238
NM_013293TRA2ATransformer 2α0.221
NM_002984CCL4Chemokine (C-C motif) ligand 40.184
NM_000577IL1RNIL-1 receptor antagonist0.174
NM_004233CD83CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)0.198
NM_020651PELI1Pellino homologue 1 (Drosophila)0.245
NM_024116MGC5306Hypothetical protein MGC53060.242
NM_005414SKILSKI-like0.244
NM_002600PDE4BPhosphodiesterase 4B, cyclic AMP–specific (phosphodiesterase E4 dunce homologue, Drosophila)0.242
NM_015675GADD45BGrowth arrest and DNA damage–inducible, β0.245
AU146791UBE2E1Ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homologue, yeast)0.268
NM_005004NDUFB8NADH dehydrogenase (ubiquinone) 1β subcomplex 8, 19 kDa0.275
NM_002166ID2Inhibitor of DNA binding 2, dominant-negative helix-loop-helix protein0.267
NM_015028TNIKTRAF2 and NCK-interacting kinase0.264
NM_000575IL1AIL-1α0.187
NM_000333ATXN7Ataxin 70.275
NM_003715VDPVesicle docking protein p1150.294
  • NOTE: Duplicate genes removed from the list.