Table 3.

Pooled multivariate RRs of renal cell cancer associated with total fluid intake and alcohol intake by other variables

Variables (no. cases)RR
RR (95% CI)
RR (95% CI)
P, test for trendP, test for between-studies heterogeneityP, test for interaction *
Total fluid
Tertile 1Tertile 2Tertile 3
BMI (kg/m2)0.78
    <25 (n = 76)1.000.84 (0.48-1.47)1.01 (0.54-1.88)0.980.99
    ≥25 (n = 126)1.001.11 (0.71-1.73)0.88 (0.54-1.43)0.540.99
History of hypertension0.46
    Yes (n = 109)1.001.16 (0.71-1.90)1.06 (0.62-1.79)0.910.65
    No (n = 93)1.000.80 (0.48-1.31)0.68 (0.39-1.19)0.170.54
Smoking0.63
    Ever (n = 122)1.001.41 (0.87-2.30)1.07 (0.63-1.82)0.940.40
    Never (n = 80)1.000.54 (0.31-0.94)0.79 (0.38-1.64)0.380.22
Alcohol (g/d)

None
0.1-4.9
≥5.0



BMI (kg/m2)0.71
    <25 (n = 102)1.000.84 (0.48-1.46)0.69 (0.26-1.80)0.540.07
    ≥25 (n = 146)1.001.10 (0.71-1.71)0.89 (0.57-1.40)0.320.61
History of hypertension0.42
    Yes (n = 127)1.000.72 (0.43-1.20)1.07 (0.66-1.74)0.230.30
    No (n = 121)1.001.31 (0.82-2.09)0.62 (0.31-1.21)0.040.18
Smoking0.91
    Ever (n = 150)1.000.98 (0.60-1.61)0.88 (0.55-1.42)0.420.86
    Never (n = 98)1.001.07 (0.66-1.73)0.81 (0.26-2.51)0.670.03
  • NOTE: The same covariates listed in Table 2 were adjusted. For total fluid, alcohol intake (continuous) was additionally adjusted.

  • * For the highest category.