Table 2.

Adjusted ORs (95% CIs) of developing gastric cancer for all subjects with H. pylori IgG seropositivity and with stratification by several factors

No. H. pylori–positive cases/controlsAdjusted OR* (95% CI)
All subjects (511 pairs)478/3835.1 (3.2-8.0)
Gender
    Men (342 pairs)327/2596.8 (3.6-12.6)
    Women (169 pairs)151/1244.6 (2.1-9.9)
Age at baseline (y)
    40-49 (77 pairs)72/527.0 (1.8-27.4)
    50-59 (235 pairs)220/1804.4 (2.2-8.7)
    60-69 (199 pairs)186/1515.4 (2.5-11.6)
Duration between blood donation and cancer diagnosis (y)
    0-4 (205 pairs)190/1447.4 (3.4-16.2)
    4-8 (181 pairs)170/1414.9 (2.2-10.9)
    ≥8 (125 pairs)118/984.5 (1.8-11.4)
Tumor location
    Upper third of stomach, including cardia (39 pairs)37/333.7 (0.2-68.4)
    Distal portion of stomach (368 pairs)344/2745.1 (3.0-8.6)
Histologic type
    Differentiated type (299 pairs)281/2235.8 (3.1-10.8)
    Undifferentiated type (159 pairs)149/1225.1 (2.1-12.3)
  • * Matched for age, gender, resident area, blood donation date, and fasting times at blood donation. Adjusted for smoking status, consumption of fish gut, green_yellow vegetables, other vegetables, fruit, green tea, body mass index, and family history of gastric cancer.